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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CAMK2A All Species: 42.42
Human Site: Y437 Identified Species: 84.85
UniProt: Q9UQM7 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9UQM7 NP_741960.1 478 54030 Y437 A Y I R I T Q Y L D A G G I P
Chimpanzee Pan troglodytes XP_001164869 479 54199 Y438 A Y I R I T Q Y L D A G G I P
Rhesus Macaque Macaca mulatta XP_001096460 479 54071 Y438 A Y I R L T Q Y M D G S G M P
Dog Lupus familis XP_853581 478 54087 Y437 A Y I R I T Q Y L D A G G I P
Cat Felis silvestris
Mouse Mus musculus Q6PHZ2 499 56351 Y437 A Y I R L T Q Y M D G S G M P
Rat Rattus norvegicus P11275 478 54096 Y437 A Y I R I T Q Y L D A G G I P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510250 634 71113 Y593 A Y I R I T Q Y V D A G G V P
Chicken Gallus gallus Q5ZKI0 479 54184 Y437 A Y I R L T Q Y M D G T G M P
Frog Xenopus laevis Q9DG02 475 53914 Y435 A Y I R L T Q Y L D S A G M P
Zebra Danio Brachydanio rerio Q6DEH3 491 55810 Y450 A Y I R L T Q Y M D V N N M P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q00168 530 59901 Y480 A Y V R L T Q Y I D K Q G H A
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q8RWL2 534 60474 S485 T R D E L K H S M T E Y G M G
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.3 88.5 99.5 N.A. 83.5 99.7 N.A. 73.8 87 86.6 84.1 N.A. 70.3 N.A. N.A. N.A.
Protein Similarity: 100 96 95.1 99.7 N.A. 90.1 100 N.A. 74.6 93.9 94.3 90.8 N.A. 80.3 N.A. N.A. N.A.
P-Site Identity: 100 100 66.6 100 N.A. 66.6 100 N.A. 86.6 66.6 73.3 60 N.A. 53.3 N.A. N.A. N.A.
P-Site Similarity: 100 100 86.6 100 N.A. 86.6 100 N.A. 100 86.6 93.3 80 N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 30.5 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 47.5 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 92 0 0 0 0 0 0 0 0 0 42 9 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 9 0 0 0 0 0 0 92 0 0 0 0 0 % D
% Glu: 0 0 0 9 0 0 0 0 0 0 9 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 25 42 92 0 9 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 84 0 42 0 0 0 9 0 0 0 0 34 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % K
% Leu: 0 0 0 0 59 0 0 0 42 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 42 0 0 0 0 50 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 84 % P
% Gln: 0 0 0 0 0 0 92 0 0 0 0 9 0 0 0 % Q
% Arg: 0 9 0 92 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 9 0 0 9 17 0 0 0 % S
% Thr: 9 0 0 0 0 92 0 0 0 9 0 9 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 9 0 9 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 92 0 0 0 0 0 92 0 0 0 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _